Our Technology
IVX037
IVX037 is a self-amplifying non-enveloped, single-positive-stranded RNA virus. It has been bioselected, targeting a novel receptor highly expressed in colorectal, gastric, ovarian, liver and other cancer types. IVX037 entered the clinic in 2023.
IVX055
IVX055 is a self-amplifying non-enveloped, single-positive-stranded RNA virus. It has been bioselected, targeting a novel receptor highly expressed in non-small cell lung and other cancer types. IVX055 is planned to enter the clinic in 2025.
Differentiated Oncolytic RNA Immunotherapy Pipeline
Scientific Presentations
Date
Conference
Title
6 November 2023
38th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)
14 August 2024
Medical Oncology Group of Australia (MOGA) 45th Annual Scientific Meeting
Pre-clinical / discovery
The company has a well resourced team at its Newcastle R&D facility working on multiple projects including:
- Assessment of IVX037 in additional cancer types and in combination with other therapies such as CAR-T cell.
- Preparation of IVX055 pre-clinical and CMC data package to enable first in patient study planned to commence in 2025
- Alternative delivery modalities
- Expanding to other cancer indications
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